WELL
PRINCIPLED
Machines That Know Why
Enabling True Artificial General Intelligence
Beyond deep learning: enabling AI to discover, not just recognize.
Beyond the Pattern
Today’s deep learning-based AI excels at pattern recognition but is fundamentally brittle, data-intensive, and incapable of genuine scientific discovery. These architectures fail catastrophically when faced with minor variations, clearly lacking the structured cognitive abilities, like abductive reasoning, necessary to autonomously hypothesize novel causal mechanisms that drive true innovation and scientific breakthroughs.
Nature’s Proof of Concept
Recent neuroscience discoveries have mapped critical aspects of the human neocortex, revealing intricate details such as: active dendrites, local Hebbian learning rules, and sophisticated cognitive maps that current AI models completely omit. These breakthroughs provide a scientifically grounded blueprint, demonstrating how structured cognitive processes like abductive reasoning can be computationally replicated.
AI That Can Think Like a Scientist
Our approach translates and integrates cutting edge neuroscience into a revolutionary AI architecture: an Abduction Coprocessor that mirrors the human neocortex's cognitive sophistication. This structured virtual neocortex actively constructs causal world models, generates original hypotheses in response to novel situations, and adapts robustly with minimal training data, thereby overcoming deep learning’s fundamental limitations and paving the path toward true Artificial General Intelligence.
About Well Principled
Our teams history of achievement.
7 Years
Building Powerful AI Models Derived from Academic Research
From Science to Software
Our expertise lies in systematically synthesizing academic research into actionable AI solutions. We've successfully built scientifically rigorous models in fields ranging from electrochemistry and advanced materials science to endocrinology, human metabolism, and consumer market dynamics. By integrating these scientific foundations into AI software, we've consistently empowered businesses to make data-informed decisions and achieve superior results.
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80+ Years
Founder experience at the Intersection of Science, Startups, and Software
Cross Disciplinary Leaders
We are a multidisciplinary team uniquely skilled in applying software engineering to complex scientific and mathematical challenges. Our backgrounds encompass human and plant biology, physics, economics, materials science, and high performance computing, complemented by strategic oversight from award-winning WashU academics and former Palantir executives. This diverse expertise enables us to rapidly translate cutting edge research into impactful technological solutions.
12+ Investors
Funded by Leading VCs and Visionary Entrepreneurs
Backed by the Best
Well Principled is proudly supported by some of the world’s most influential venture capital firms and technology leaders. Our investors include prestigious firms such as Peter Thiel’s Founders Fund, Joe Montana’s Liquid 2 Ventures, and YCombinator. Complemented by specialized bioscience investors like Cultivation Capital and global VC powerhouses such as Global Founders Capital (GFC), our funding reflects deep industry confidence and strategic support.